The geopolitical dynamics of Southeast Asia after the COVID-19 pandemic have experienced significant changes, creating a new landscape influenced by economic, political and social factors. Countries in the region face challenges and opportunities that affect interstate relations and their position in the global arena. One of the crucial aspects in this dynamic is the shift in economic power. Countries such as Vietnam and Indonesia, which have managed the impact of the pandemic relatively well, have become the center of attention in the region. Foreign direct investment (FDI) and supply chain shifts are increasingly flowing to these countries, making them alternatives to China in production and manufacturing. This was accompanied by increased regional trade cooperation, especially through ASEAN, which sought to restore economic growth. However, tensions between China and Western countries, especially the US, also have an impact on Southeast Asian geopolitics. China is trying to expand its influence through the Belt and Road Initiative (BRI), while the US is trying to strengthen its regional position by establishing strategic alliances through the Quad and Aukus. Countries in Southeast Asia are caught in this rivalry, with the challenge of balancing relations with both great powers. Conflict in the South China Sea remains a major issue. A number of countries, including the Philippines and Vietnam, continue to fight for rights to natural resources in contested areas. Agreements, such as the Declaration on Conduct in the South China Sea (DOC), appear to be less effective, giving rise to tensions and the potential for military conflict. Domestic politics also influences this dynamic. Elections in various countries such as Thailand, Malaysia and the Philippines create new opportunities and challenges. Ruling political parties often have to deal with public demands for transparency and accountability, especially after the pandemic has worsened economic and social conditions. Social issues, including health and food security, are becoming new priorities for the government. Cooperation between countries to tackle climate change and subsequent pandemics is essential. Green initiatives and digital technology play a role as triggers for innovation and sustainable development in the region. Post-pandemic digital transformation is also changing the way Southeast Asian countries interact with each other. The emergence of digital platforms enables more effective collaboration in the education, health and economic sectors. Countries are starting to explore new technologies to improve the efficiency of government and public services. Public participation in geopolitical issues also appears to be increasing. The younger generation is increasingly active in social and political movements, bringing changes in perspective that impact government policy. The use of social media and wider access to information provides a platform for their voice in the decision-making process. Public health, which has been in the spotlight during the pandemic, also plays a role in geopolitics. Investments in health infrastructure show how countries are prioritizing preparedness to face future crises. Cooperation between countries in controlling infectious diseases and distributing vaccines is an important focus for increasing ASEAN’s resilience. Sustainability is a central theme in post-pandemic development in Southeast Asia. Countries are starting to adopt sustainable economic principles to reduce negative impacts on the environment and ensure that economic growth can be achieved without sacrificing natural resources and people’s quality of life. Thus, the geopolitical dynamics of post-pandemic Southeast Asia create a complex arena. These factors require countries in the region to adapt quickly and strategically in order to survive and thrive in an ever-changing global order. As a result, international collaboration, innovation and responses to socio-economic challenges will be key to shaping a better future for the region.